What does hyaline cast in urinalysis mean?
Casts are clusters of urinary sediment elements (red blood cells, white blood cells, fat bodies, etc.) wrapped in a protein matrix. Cast formation necessarily occurs in the kidney tubules, and the the contents of the casts indicate the nature of the abnormalities occurring in the kidney itself.
What does high hyaline casts in urine mean?
The presence of hyaline casts typically indicates a decreased or sluggish urine flow, which can be a result of strenuous exercise, diuretic medications, severe vomiting, or fever.
What do hyaline cells do?
The most obvious cells are the large hyaline cells, which have thickened bands of supporting material, and often haves pores. These cells are dead at maturity, and serve to retain water. Between the hyaline cells are small slender chlorophyllose cells, so named because they contain the chlorophyll and manufacture food.
Can dehydration cause hyaline casts?
Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and as such, they may be seen in normal individuals in dehydration or vigorous exercise.
Is it normal to have hyaline casts in urine?
Very few casts are seen in the urine of a person without renal disease. A common exception is hyaline casts, which may often be seen in healthy patients or can be present after strenuous exercise or diuretic use. A significant number of urinary casts usually indicates the presence of renal disease.
What is the normal range for hyaline casts in urine?
Casts: Casts are formed in the tubules of they kidney when the tubules secrete a protein called Tamm-Horsfall protein. The origin of the casts causes them to take on a tubular or hotdog-like shape. These casts are known as hyaline casts and can be present in normal adults on the order of 0-5 per LPF.
How do you lower hyaline casts?
Reduced lighting is essential to see hyaline casts in urine sediment preparations. Lighting can be reduced by lowering the substage condenser (or close the iris diaphragm).
What is hyaline made of?
Hyaline cartilage is found in the synovial joints and assists the motion of joints. It is composed of chondrocytes and extracellular matrix. Chondrocytes plays a major role in the organization of extracellular matrix, which is responsible for the biomechanical properties of cartilage tissue.
What is hyaline in biology?
Hyaline cartilage is the glass-like (hyaline) and translucent cartilage found on many joint surfaces. It is also most commonly found in the ribs, nose, larynx, and trachea. Hyaline cartilage is pearl-grey in color, with a firm consistency and has a considerable amount of collagen.
Are hyaline casts in urine normal?
What does the presence of casts in urine mean?
Granular casts are a sign of many types of kidney diseases. Red blood cell casts mean there is a microscopic amount of bleeding from the kidney. They are seen in many kidney diseases. Renal tubular epithelial cell casts reflect damage to tubule cells in the kidney.
What is hyaline cartilage?
Hyaline cartilage is a type of connective tissue found in areas such as the nose, ears, and trachea of the human body. The word hyaline means “glass-like”, and hyaline cartilage is a glossy, greyish-white tissue with a uniform appearance.
What are hyaline membranes?
Hyaline membranes are accumulations of proteinaceous alveolar exudates at the periphery of the alveoli. These become adherent to the alveolar septa and are seen to outline the alveolar spaces (Fig. 3.3 ).
What are hyaline casts?
Hyaline casts are the simplest and most common type of urinary cast. Urinary casts are microscopic clusters of urinary particles, such as cells, fat bodies, or microorganisms, wrapped in a protein matrix and found in the urine.
What causes hyaline casts in the urine?
A few hyaline casts may occasionally be found in normal urine, and hyaline casts may be seen after strenuous exercise, during fever, or when undergoing diuretic therapy. Greater numbers of hyaline casts may be seen in association with proteinuria of prerenal (e.g., overflow proteinuria as in myeloma) or renal (e.g., glomerular disease) origin.