What is DU testing?
Weak D (Du) testing – Testing that is done to detect a weak Rh type. Forward typing- A blood typing procedure whereby patient red blood cells are mixed with Anti-A and Anti-B reagents.
What does Du positive mean?
Your Rh factor — “Du,” also called “weak D” — is a weakly positive Rh D factor. Less than 1 percent of people have this. Blood banks have not always been consistent in how this is reported.
What does it mean to be a rhesus D positive?
If you’re rhesus positive (RhD positive), it means that a protein (D antigen) is found on the surface of your red blood cells. Most people are RhD positive. If you’re rhesus negative (RhD negative), you do not have the D antigen on your blood cells.
What is DU in blood?
Du is the phenotypic term used to denote a weakened expression of the D antigen. Du originally defined as those red cells reacting with anti-D only when a more sensitive indirect antiglobulin test was used. Du phenotype can arise from three different genetic situations.
Why Du test is done?
The reason for performing the Du test early in pregnancy is to avoid mis-interpreting the cause of a positive fetal cell screening test at the time of delivery. In addition to prenatal patients, newborn babies are also tested for Du if they type as D negative.
What is Rh factor?
Overview. Rhesus (Rh) factor is an inherited protein found on the surface of red blood cells. If your blood has the protein, you’re Rh positive. If your blood lacks the protein, you’re Rh negative.
What is Rh-negative DU positive?
The term Rh positive is used to denote red cells that carry the D (Rh) antigen or its variant Du. Red cells that have neither D nor Du on their membranes are termed Rh negative. With the exception of A and B, the most important of all blood group antigens is undoubtedly D.
Can you go from Rh-negative to Rh positive?
For example: If a woman who is Rh negative and a man who is Rh positive conceive a baby, the fetus may have Rh-positive blood, inherited from the father. (About half of the children born to an Rh-negative mother and Rh-positive father will be Rh-positive.)
Is rhesus positive a good thing?
Rh positive is the most common blood type. Having an Rh negative blood type is not an illness and usually does not affect your health. However, it can affect your pregnancy. Your pregnancy needs special care if you’re Rh negative and your baby is Rh positive (Rh incompatibility).
Can rhesus positive marry rhesus positive?
Blood group compatibility for marriage is limited to possible Rh factor incompatibility during pregnancy. And that is further limited to pregnancy where both partners are the biological parents.
Why is DU test done?
Is Rh du positive or negative blood type?
The Rh, Du blood phenotype occurs rarely in the white population (0.23-0.60%). Its clinical significance is whether it should be considered it as Rh positive or negative. A pregnant woman with blood type Rh, Du (+), who delivered an Rh D (+) baby and was not given Rh immune globulin is presented. Th …
What is the D variant of rhesus?
D positive patients were termed Rhesus-positive. In 1946, a quantitative variant with a weakly expressed D antigen was discovered and termed “Du”. This variant, now called “weak D”, is of clinical and diagnostic importance. Since 1953, is has been clear that there are also qualitative variants of the D antigen.
What is the difference between rhesus positive and Rh negative?
The clinically essential difference between Rhesus positive and Rhesus negative hinges on the presence or absence of the RhD protein in the erythrocyte membrane (D positive resp. D negative). It is unusual for erythrocyte or other cell proteins to be lacking entirely in many humans.
What is the history of D positive rhesus?
The D antigen, discovered in 1939, was the first Rhesus antigen to be described. D positive patients were termed Rhesus-positive. In 1946, a quantitative variant with a weakly expressed D antigen was discovered and termed “Du”. This variant, now called “weak D”, is of clinical and diagnostic importance.