What is stereochemistry and isomerism?
In stereochemistry, stereoisomerism, or spatial isomerism, is a form of isomerism in which molecules have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.
Is isomerism and Stereoisomerism same?
Structural isomers have the same molecular formula but a different bonding arrangement among the atoms. Stereoisomers have identical molecular formulas and arrangements of atoms. They differ from each other only in the spatial orientation of groups in the molecule.
How do you remember stereoisomers?
One quick way to tell if two molecules are stereoisomers is if they have the same core IUPAC name but differ in their cis/trans, E/Z, or (R)/(S) designations.
What is stereochemistry in organic chemistry?
STEREOCHEMISTRY: DEFINITION. The branch of chemistry which deals with three dimensional structure of molecule and their effect on physical and chemical properties is known as stereochemistry. To represent molecule as three dimensional object we need at least one carbon sp3- hybridized.
How do you identify isomers?
You can tell them apart by their bonding patterns and how they take up three-dimensional space. Identify structural (constitutional) isomers by their bonding patterns. The atoms of the compounds are the same but they are connected in such a way as to make different functional groups.
What are Fischer projections used for?
Fischer projections are a convenient way to depict chiral molecules (see optical activity) and distinguish between pairs of enantiomers (see racemic mixture). They are most often used to depict isomers of the sugars.
What are positional isomers?
Positional isomers are constitutional isomers, with the same carbon skeleton and will have the same functional group. They differ from each other in the position of the functional groups on the carbon chain.
What is optical isomerism?
Optical isomers are two compounds which contain the same number and kinds of atoms, and bonds (i.e., the connectivity between atoms is the same), and different spatial arrangements of the atoms, but which have non-superimposable mirror images.
What is difference between enantiomers and diastereomers?
Enantiomers are non-superimposable mirror images of each other. Enantiomers are mirror images of each other which are known as stereoisomers. Diastereomers are also non-superimposable but are not mirror images of each other. Diastereomers are not mirrored images of each other which are known as stereoisomers.
What is stereochemistry used for?
Stereochemistry is a subdiscipline of chemistry. It is involved in the study of relative spatial arrangement of atoms that form the structure of molecules and their manipulation. Chiral molecule is an important branch of stereochemistry.
Why do we need stereochemistry?
Stereochemistry is of critical importance to drug action because the shape of a drug molecule is an important factor in determining how it interacts with the various biological molecules (enzymes, receptors, etc.) that it encounters in the body.