Can metoprolol cause falls?
Medications that might contribute to hypotension, dizziness, and falls: Metoprolol (which might also contribute to bradycardia) Amlodipine (which might also contribute to ankle edema)
Can furosemide cause falls?
Certain blood pressure medications may increase your risk for falling—but it’s a small risk with these drugs. Clonidine (Catapres), diuretics (e.g., furosemide, hydrochlorothiazide, chlorthalidone), and ACE inhibitors (e.g., lisinopril, ramipril, enalapril) are the blood pressure medications that carry a higher risk.
Do beta blockers increase fall risk?
Conclusion: Our study suggests that use of a nonselective β-blocker, contrary to selective β-blockers, is associated with an increased fall risk in an older population. In clinical practice, β-blockers have been shown effective for a variety of cardiovascular indications.
What drug makes you fall over?
Medications that suppress the central nervous system are among those most likely to contribute to falling, as they reduce alertness and cause slower reactions and movements. These include: Anti-anxiety drugs, such as diazepam (Valium) and lorazepam (Ativan) Diphenhydramine (Benadryl), an older antihistamine.
What to do if elderly keeps falling?
Call 911 and keep your loved one as warm, comfortable and still as possible until help arrives. If they aren’t badly hurt and they want to get up, proceed slowly. Stop at any point if they become stuck, experience pain or become too tired to get all the way up. Find two sturdy chairs.
What drugs increase fall risk?
Medications that increase your risk of falling
- Anti-anxiety drugs, such as diazepam (Valium) and lorazepam (Ativan)
- Diphenhydramine (Benadryl), an older antihistamine.
- Prescription medications to treat overactive bladder, such as oxybutynin (Ditropan) and tolterodine (Detrol).
- Tricyclic antidepressants.
Why are diuretics a fall risk?
Alternatively changes in diuretic drugs decrease blood pressure and may lead to dizziness and subsequent falls.
Can propranolol cause falls?
A recent meta-analysis published in the British Journal of Clinical Pharmacology concluded that the use of non-selective beta-blockers, such as propranolol or carvedilol, in elderly populations is associated with increased risk of falling.
What are the side effects of furosemide?
This medication may cause dehydration and electrolyte imbalance. Tell your doctor right away if you have any of these unlikely but serious side effects: muscle cramps, weakness, unusual tiredness, confusion, severe dizziness, fainting, drowsiness, unusual dry mouth/thirst, nausea, vomiting, fast/irregular heartbeat.
What is lipophorin?
This lipoprotein is termed lipophorin. Lipophorins can be classified as low-density, high-density, and very-high-density lipophorins, depending on their lipid loading. The main lipid components are 1,2-diacylglycerols together with hydrocarbons, phospholipids, and sterols. It has also two apolipoproteins: apolipoprotein I and apolipoprotein II.
Which drugs are lipophilic drugs?
A number of lipophilic drugs such as naloxone, buprenorphine, testosterone, and 17a-ethinylestradiol have shown to be completely absorbed nasally in animal models [11, 16].
What are apolipoproteins in lipophorin?
All lipophorin particles possess two apolipoproteins, termed apolipophorin I (apoLp-I) and apolipophorin II (apoLp-II). ApoLp-I and apoLp-II are integral components of the lipophorin particle and cannot be removed without destruction of lipophorin particle integrity.
What are lipophilic prodrugs used for?
Lipophilic prodrugs are also used to enhance ocular absorption. Isopropyl esters offer the best pharmacokinetic characteristics for a number of prostaglandins that are intended for the use in ocular application, especially in animal models. Latanoprost and travoprost ( Fig. 8.15) are representatives of isopropyl ester prodrugs.