Does DMSO cause birth defects?
DMSO use has been associated with the following potential side effects: skin rash, erythema, itchiness, scaly skin, skin thickening, hives, blistering, skin pain, nausea, diarrhea, headache, garlic-like taste in mouth, garlic-like breath, garlic-like body odor, transient hemolysis, dizziness, sedation, kidney injury.
What are the dangers of DMSO?
To make matters worse, DMSO is easily absorbed through the skin, so it carries these impurities rapidly into the body. Some side effects of taking DMSO include skin reactions, dry skin, headache, dizziness, drowsiness, nausea, vomiting, diarrhea, constipation, breathing problems, and allergic reactions.
Is DMSO a safe solvent?
Abstract. Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity in the 1960s, later, the FDA classified DMSO in the safest solvent category.
What happens if you drink DMSO?
Some side effects of taking DMSO by mouth or applying it to the skin include skin reactions, dry skin, headache, dizziness, drowsiness, nausea, vomiting, diarrhea, constipation, breathing problems, vision problems, blood problems, and allergic reactions. DMSO also causes a garlic-like taste, and breath and body odor.
How long does DMSO stay in system?
Both DMSO and dimethyl sulfide are extensively and rapidly distributed to all areas of the body after oral, intravenous, and topical administration. The half-life of the parent compound and its metabolite is nine hours.
Why is DMSO toxic to cells?
The suggested mechanism for DMSO cytotoxicity is the effect on the physical properties of the phospholipids in membranes. As an amphipathic solvent, DMSO can interact with the plasma membrane allowing pores formation, which contribute to decrease membrane selectivity and increases cell permeability [14].
Is DMSO poisonous to humans?
DMSO can also cause a deadly reaction when used in high concentrations. Using DMSO by mouth can cause: Dizziness. Drowsiness.
Is DMSO safe during pregnancy?
Pregnant women and women who are breastfeeding should not use DMSO, since little is known about its possible effects on the fetus or infant. You should also not use DMSO without talking to your doctor if you have: Diabetes.
How much DMSO is toxic?
Rule of thumb: 0.1% DMSO is considered to be safe for almost all cells. 0.5% DMSO as the final concentration has been used widely for cell culture without cytotoxicity. 1% DMSO doesn’t cause any toxicity to some cells but 0.5% DMSO is recommended.