How do you give diltiazem IV?

How do you give diltiazem IV?

Intravenous Administration A common infusion dilution is 125 mg of diltiazem injection added to 100 mL of an appropriate diluent to give a final concentration of 125 mg/125 mL (1 mg/mL). For adult patients, infuse at an initial rate of 10 mg/hr, and increase if necessary to 15 mg/hr.

How fast do you push IV Cardizem?

In the standard IV push group, diltiazem will be administered at a dose of 0.25 mg/kg, to a max dose of 25 mg, over 2 minutes.

How do you convert PO to IV diltiazem?

Diltiazem IV to Oral Dose Conversion

1. 3 mg/hr IV = 120 mg daily (in 4 divided doses using IR dosage forms; e.g., 30 mg every 6 hrs)
2. 5 mg/hr IV = 180 mg daily (in 4 divided doses using IR dosage forms)
3. 7 mg/hr IV = 240 mg daily (in 4 divided doses using IR dosage forms)

How do you run a Cardizem drip?

An initial Cardizem I.V. Bolus dose may be ordered by the physician. The initial dose should be 0.25 mg/kg actual body weight as a bolus administered over 2 minutes. If response is inadequate, a second bolus dose may be administered after 15 minutes.

What is diltiazem drip?

Diltiazem is used to control rapid heartbeats or abnormal heart rhythms. It belongs to a group of drugs called calcium channel blocking agents. Diltiazem affects the movement of calcium into the cells of the heart and blood vessels.

How do you titrate drips?

You’d calculate the titrations like this: 5 x 0.3 = 1.5 ml/hour (5 mcg/minute) 15 x 0.3 = 4.5 ml/hour (15 mcg/minute) 20 x 0.3 = 6 ml/hour (20 mcg/minute) …and so on. Some drugs (such as lidocaine and procainamide) are ordered as mg/minute.

What is a diltiazem drip?

Descriptions. Diltiazem is used to control rapid heartbeats or abnormal heart rhythms. It belongs to a group of drugs called calcium channel blocking agents. Diltiazem affects the movement of calcium into the cells of the heart and blood vessels.

Can calcium channel blockers be given IV?

Clevidipine is an intravenous (IV) dihydropyridine calcium-channel blocker (CCB) with a rapid onset of action (2–4 min) and a short duration of action (5–15 min). This agent is approved for the reduction of blood pressure (BP) when oral therapy is not feasible or not desirable.

How do you titrate down diltiazem drip?

When actually making the switch, give the first oral dose about 1 hour before you plan to stop the drip. After the first hour, slowly titrate down the diltiazem drip by 2.5 mg/hr increments until 0. By then, the diltiazem should have time to be absorbed and distributed (time to Tmax is approximately 1 to 1.5 hours).

What is the half life of IV diltiazem?

After the 10 and 15 mg/hr infusions of diltiazem, mean +/- SD elimination half-life was 6.8 +/- 1.8 and 6.9 +/- 1.5 hours, volume of distribution was 411 +/- 151.8 and 299 +/- 70.8 I, and systemic clearance was 42 +/- 12.4 and 31 +/- 8.3 l/hr, respectively.

How long do you take diltiazem drip?

What is diltiazem drip used for?